Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591021 | 1.00 | MEN1 (0.54) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6590529 | 0.84 | KMT2A (0.48) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6080952 | 0.84 | KMT2A (0.48) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL4971979 | 0.84 | APP (0.50) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6594275 | 0.81 | MEN1 (0.50) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL6594282 | 0.81 | MEN1 (0.50) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL6080455 | 0.80 | HCAR3 (0.47) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL28323574 | 0.80 | GPR35 (0.42) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL9069976 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL28423586 | 0.77 | MEN1 (0.40) | MEN1KMT2ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |