Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | FADS1 | O60427 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | F12 | P00748 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746736 | 0.90 | PLAU (0.55) | MEN1KMT2AALDH1A1HPGDMAOB | |
| SCHEMBL2957280 | 0.87 | MEN1 (0.61) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL6592828 | 0.84 | MAPT (0.61) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6589803 | 0.84 | FADS1 (0.58) | MEN1KMT2AFADS1MAOBF12 | |
| SCHEMBL6815342 | 0.83 | FADS1 (0.56) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL14112955 | 0.83 | HPGD (0.69) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL6285639 | 0.82 | TMPRSS4 (0.67) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL5583049 | 0.82 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1HPGDTDP1 | |
| SCHEMBL5222453 | 0.82 | RAF1 (0.60) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL18160386 | 0.81 | MEN1 (0.69) | MEN1KMT2AALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041272-B | 2- (2-chlorphenyl) quinazoline-4 (3H) -ketone derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-30 | — | — | CN | disclosed |
| CN-110041272-A | 2- (2- chlorphenyl) quinazoline -4 (3H) -one analog derivative and its preparation method and application | 中国人民解放军军事科学院军事医学研究院 | 2019-07-23 | — | — | CN | disclosed |
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |