Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 8/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 8/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.32 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595172 | 0.81 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7152613 | 0.76 | GRIA1 (0.51) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6596000 | 0.72 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6598164 | 0.69 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6598151 | 0.69 | FPR2 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6598565 | 0.66 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6597953 | 0.65 | GRIK1 (0.36) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6602742 | 0.64 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6601414 | 0.64 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6605387 | 0.63 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156044-B1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-1156044-A1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |