Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598196 | 0.83 | MAPT (0.51) | KDM4EALDH1A1MAPTHPGDCTSK | |
| SCHEMBL3453428 | 0.79 | MAPT (0.48) | KDM4EALDH1A1MAPT | |
| SCHEMBL2077223 | 0.79 | MAPT (0.55) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL2077222 | 0.79 | MAPT (0.51) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL513858 | 0.77 | MAPT (0.50) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL2347506 | 0.77 | CTSK (0.54) | KDM4ELMNAALDH1A1HPGDKHK | |
| SCHEMBL13036137 | 0.76 | MAPT (0.49) | KDM4ELMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL20091942 | 0.76 | CTSK (0.50) | KDM4EALDH1A1HPGDKHKCTSK | |
| SCHEMBL3357016 | 0.75 | ALDH1A1 (0.60) | KDM4ELMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL30449208 | 0.75 | ALDH1A1 (0.60) | KDM4ELMNAALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373264-B1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LTD (GB) | 2004-12-22 | — | — | EP | disclosed |
| US-6821972-B2 | ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS | PFIZER INC. | 2004-11-23 | — | — | US | disclosed |
| EP-1373264-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | Pfizer Limited (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-20030069291-A1 | 3-heterocyclylpropanohydroxamic acid PCP inhibitors | PFIZER INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2002079200-A1 | 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LIMITED (GB) | 2002-10-10 | — | — | WO | disclosed |
| US-4442097-A | BACTERICIDES, FUNGICIDES | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | disclosed |
| US-4442096-A | BACTERICIDES, FUNGICIDES | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | disclosed |
| US-4442095-A | BACTERICIDES, FUNGICIDES | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069291-A1 | 3-heterocyclylpropanohydroxamic acid PCP inhibitors | PAH, CYP2F1, CYP7A1 | KDM4E 1708/4885LMNA 1661/4885ALDH1A1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.