Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5171836 | 0.91 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL3962933 | 0.81 | CYP19A1 (0.48) | CYP19A1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL14745993 | 0.80 | IDO1 (0.39) | CYP19A1NOS1 | |
| SCHEMBL75303 | 0.77 | LOXL2 (0.45) | ALDH1A1KDM4EHRH4 | |
| SCHEMBL7807147 | 0.77 | KDM4E (0.55) | CYP19A1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL28761405 | 0.77 | CYP19A1 (0.46) | CYP19A1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL8629980 | 0.76 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL9486575 | 0.75 | CYP19A1 (0.49) | CYP19A1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2367117 | 0.74 | TSHR (0.47) | CYP19A1ALDH1A1MAPTPOLBKCNJ1 | |
| SCHEMBL6597520 | 0.74 | CYP19A1 (0.51) | CYP19A1ALDH1A1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |