Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762848 | 0.85 | NR1H4 (0.35) | NR1H4GPBAR1HTR2BSLC6A9 | |
| SCHEMBL6594562 | 0.85 | GPBAR1 (0.32) | GPBAR1 | |
| SCHEMBL6596749 | 0.82 | GPBAR1 (0.36) | NR1H4GPBAR1SLC6A9 | |
| SCHEMBL8492769 | 0.81 | POLB (0.35) | NR1H4 | |
| SCHEMBL8461471 | 0.81 | HCRTR2 (0.31) | L3MBTL1 | |
| SCHEMBL8493465 | 0.79 | SLC6A9 (0.35) | L3MBTL1HTR2BSLC6A9 | |
| SCHEMBL6595018 | 0.78 | NPC1 (0.38) | NR1H4GPBAR1 | |
| SCHEMBL8607786 | 0.77 | STAT3 (0.45) | — | |
| SCHEMBL6054858 | 0.76 | CACNA1B (0.39) | — | |
| SCHEMBL6600395 | 0.75 | NPC1 (0.34) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | claimed |
| US-6297198-B1 | COMPOUNDS WITH SULFUR GROUPS ON ISOXAZOLE RINGS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-10-02 | — | — | US | claimed |
| EP-0901479-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1999-03-17 | — | — | EP | claimed |
| WO-1997043270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | claimed |
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | disclosed |
| EP-0901479-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | disclosed |