Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 12/20 | 0.35 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.33 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762928 | 0.89 | SMURF2 (0.36) | NR1H4SMURF2SMURF1GPBAR1 | |
| SCHEMBL8492769 | 0.88 | POLB (0.35) | NR1H4 | |
| SCHEMBL6595822 | 0.85 | NR1H4 (0.32) | NR1H4SLC6A9GPBAR1HTR2B | |
| SCHEMBL8762913 | 0.82 | SMURF2 (0.38) | NR1H4SMURF2SMURF1GPBAR1 | |
| SCHEMBL8588447 | 0.80 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL8493465 | 0.80 | SLC6A9 (0.35) | SLC6A9KCNH2HTR2B | |
| SCHEMBL8822174 | 0.80 | SMURF2 (0.38) | NR1H4SMURF2SMURF1GPBAR1 | |
| SCHEMBL8763780 | 0.79 | BCAT2 (0.39) | SMURF2SMURF1GPBAR1 | |
| SCHEMBL8492955 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL8607786 | 0.78 | STAT3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | claimed |