Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1193597 | 0.99 | KMT2A (0.49) | KMT2APABPC1ATMALDH1A1LMNA | |
| SCHEMBL6599925 | 0.85 | KMT2A (0.42) | KMT2APABPC1ATMALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1194570 | 0.84 | KMT2A (0.41) | KMT2APABPC1ATMALDH1A1LMNA | |
| SCHEMBL6595709 | 0.84 | ALDH1A1 (0.38) | KMT2APABPC1ATMALDH1A1LMNA | |
| SCHEMBL6599975 | 0.83 | CYP1A2 (0.54) | ALDH1A1LMNAKDM4ESMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL1194041 | 0.83 | ALDH1A1 (0.38) | KMT2APABPC1ATMALDH1A1LMNA | |
| SCHEMBL6597984 | 0.82 | MAPK8 (0.39) | KMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1194183 | 0.82 | LMNA (0.56) | KMT2AALDH1A1LMNAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7070348 | 0.81 | HSP90AA1 (0.44) | KMT2AALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1194003 | 0.81 | MAPK8 (0.39) | KMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |