Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | NAMPT | P43490 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598031 | 0.82 | F2 (0.57) | ALDH1A1EPHX2 | |
| SCHEMBL6595615 | 0.82 | HPGD (0.57) | FAAHNAMPT | |
| SCHEMBL6595620 | 0.82 | HPGD (0.57) | FAAHNAMPT | |
| SCHEMBL1003906 | 0.82 | SRD5A1 (0.47) | FAAHALDH1A1KDM4EEPHX2 | |
| SCHEMBL12509353 | 0.81 | FAAH (0.67) | FAAHNAMPTALDH1A1 | |
| SCHEMBL8417473 | 0.81 | ALDH1A1 (0.53) | FAAHALDH1A1KDM4E | |
| SCHEMBL12509041 | 0.80 | EPHX2 (0.54) | NAMPTEPHX2 | |
| SCHEMBL8101559 | 0.80 | NAMPT (0.49) | FAAHNAMPTALDH1A1KDM4EEPHX2 | |
| SCHEMBL17730107 | 0.80 | NAMPT (0.63) | FAAHNAMPTEPHX2 | |
| SCHEMBL6599783 | 0.80 | GAA (0.57) | ALDH1A1KDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981526-B1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-02-25 | — | — | EP | disclosed |
| EP-0981526-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-01 | — | — | EP | disclosed |
| WO-1997041119-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |