Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594843 | 1.00 | TP53 (0.57) | TP53HTTEPHX1LMNARECQL | |
| SCHEMBL6599116 | 0.82 | SLC6A3 (0.42) | TP53HTTLMNAHPGDALDH1A1 | |
| SCHEMBL6597123 | 0.76 | SLC6A2 (0.41) | LMNAHPGDALDH1A1ALOX15MEN1 | |
| SCHEMBL8189527 | 0.71 | LMNA (0.41) | LMNAPKMALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13483598 | 0.68 | LMNA (0.56) | TP53HTTEPHX1LMNARECQL | |
| SCHEMBL3178511 | 0.67 | LMNA (0.55) | TP53HTTEPHX1LMNARECQL | |
| SCHEMBL3178518 | 0.67 | LMNA (0.55) | TP53HTTEPHX1LMNARECQL | |
| SCHEMBL6916553 | 0.66 | CHRM3 (0.48) | LMNAMEN1KMT2A | |
| SCHEMBL14491528 | 0.66 | HDAC4 (0.60) | TP53HTTEPHX1LMNAHPGD | |
| SCHEMBL14491529 | 0.66 | HDAC4 (0.60) | TP53HTTEPHX1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915867-B1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOD CONSEILS RECH APPLIC (FR) | 2004-10-06 | — | — | EP | claimed |
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |