SCHEMBL6596642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9300170	0.89	CA2 (0.46)	CES2CES1TSHRALDH1A1CA2
	SCHEMBL219773	0.80	CA2 (0.62)	CES2CES1TSHRTRPA1ALDH1A1
	SCHEMBL1043336	0.80	MEN1 (0.50)	ALDH1A1LMNAGAAHTTMEN1
	SCHEMBL28356819	0.80	CA2 (0.62)	CA2CAMK2ALMNAGAAFNTA
	SCHEMBL348419	0.78	CES2 (0.47)	CES2CES1TSHRTRPA1ALDH1A1
	SCHEMBL3823253	0.78	NPC1 (0.52)	ALDH1A1LMNAHTTMEN1KMT2A
	SCHEMBL1718199	0.78	CA2 (0.64)	CES2CES1TSHRTRPA1ALDH1A1
	SCHEMBL28844188	0.78	GAA (0.53)	ALDH1A1LMNAGAAHTTKMT2A
	SCHEMBL9772466	0.78	CTBP2 (0.52)	ALDH1A1LMNAGAAMEN1KMT2A
	SCHEMBL38652216	0.78	ALDH1A1 (0.52)	ALDH1A1CA2LMNAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.