Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603601 | 0.83 | KMT2A (0.49) | ALDH1A1KMT2AOPRK1HTTMEN1 | |
| SCHEMBL6846654 | 0.81 | KMT2A (0.51) | ALDH1A1ELANEKMT2ATXNRD1TXNRD3 | |
| SCHEMBL6599742 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2AOPRK1HTTABCG2 | |
| SCHEMBL4659474 | 0.80 | ELANE (0.50) | ALDH1A1ELANEKMT2ATXNRD1TXNRD3 | |
| SCHEMBL2910393 | 0.77 | ALDH1A1 (0.67) | ALDH1A1ELANEKMT2ATXNRD1TXNRD3 | |
| SCHEMBL6201684 | 0.75 | KDM4E (0.50) | ALDH1A1ELANEKMT2AMEN1 | |
| SCHEMBL1257817 | 0.74 | ELANE (0.72) | ALDH1A1ELANEKMT2AOPRK1ABCG2 | |
| SCHEMBL2906892 | 0.74 | ALDH1A1 (0.60) | ALDH1A1ELANEKMT2AABCG2MEN1 | |
| SCHEMBL5909911 | 0.72 | MEN1 (0.56) | ALDH1A1ELANEKMT2ATXNRD1TXNRD3 | |
| SCHEMBL23877259 | 0.72 | MYC (0.44) | ALDH1A1KMT2AMEN1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |