Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596427 | 0.89 | UTS2R (0.63) | UTS2R | |
| SCHEMBL6595055 | 0.87 | UTS2R (0.64) | UTS2R | |
| SCHEMBL6596373 | 0.87 | UTS2R (0.50) | UTS2RCCR3 | |
| SCHEMBL6596912 | 0.83 | UTS2R (0.59) | UTS2R | |
| SCHEMBL6948683 | 0.77 | UTS2R (0.80) | UTS2R | |
| SCHEMBL6944246 | 0.77 | UTS2R (0.80) | UTS2R | |
| SCHEMBL17152608 | 0.76 | BACE1 (0.53) | — | |
| SCHEMBL6597043 | 0.73 | UTS2R (0.62) | UTS2R | |
| SCHEMBL6597270 | 0.73 | UTS2R (0.61) | UTS2R | |
| SCHEMBL6594029 | 0.73 | UTS2R (0.55) | UTS2RCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-B1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | claimed |
| US-6514970-B1 | Pyrrolidines such as benzo(b)thiophene-2-carboxylic acid ((S)-1-((S)-1-(4-(1-benzyl-piperidin-4-yloxy)-3-chloro-benzyl)-pyrrolidin-3 -ylcarbamoyl)-3- methyl-butyl)-amide | SMITHKLINE BEECHAM CORPORATION | 2003-02-04 | — | — | US | claimed |
| EP-1246619-B1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6514970-B1 | Pyrrolidines such as benzo(b)thiophene-2-carboxylic acid ((S)-1-((S)-1-(4-(1-benzyl-piperidin-4-yloxy)-3-chloro-benzyl)-pyrrolidin-3 -ylcarbamoyl)-3- methyl-butyl)-amide | SMITHKLINE BEECHAM CORPORATION | 2003-02-04 | — | — | US | disclosed |