Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594388 | 0.85 | RAB9A (0.54) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL4199035 | 0.80 | HTT (0.54) | RAB9AKMT2AALDH1A1NPSR1ACHE | |
| SCHEMBL8519147 | 0.80 | RAB9A (0.70) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL22356003 | 0.80 | RAB9A (0.70) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL6450091 | 0.78 | RAB9A (1.00) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL2203220 | 0.78 | RAB9A (0.73) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL13774087 | 0.78 | RAB9A (0.73) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL8600195 | 0.77 | RAB9A (0.66) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL3059076 | 0.77 | ACHE (0.68) | RAB9AKMT2AALDH1A1PKMGAA | |
| SCHEMBL723132 | 0.77 | RAB9A (0.66) | RAB9AKMT2AALDH1A1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244663-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-08-25 | — | — | EP | disclosed |