Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595280 | 0.90 | LMNA (0.31) | LMNA | |
| SCHEMBL6591548 | 0.77 | LMNA (0.31) | LMNA | |
| SCHEMBL6597582 | 0.75 | MAOA (0.34) | — | |
| SCHEMBL5424199 | 0.71 | LMNA (0.38) | LMNA | |
| SCHEMBL30178495 | 0.71 | LMNA (0.38) | LMNA | |
| Ethylene Glycol SCHEMBL6597178 | 0.68 | MAOA (0.44) | — | |
| SCHEMBL5153336 | 0.67 | MAOA (0.47) | LMNA | |
| SCHEMBL7563021 | 0.67 | LMNA (0.43) | LMNA | |
| SCHEMBL3598536 | 0.66 | MAOA (0.36) | — | |
| SCHEMBL29391079 | 0.66 | CES2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |