Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.73 |
| ▸ | HTR1A | P08908 | 6/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352691 | 0.84 | DRD4 (1.00) | DRD4HTR1ADRD2DRD3 | |
| SCHEMBL6352689 | 0.84 | DRD4 (1.00) | DRD4HTR1ADRD2DRD3 | |
| SCHEMBL6360190 | 0.76 | DRD4 (0.84) | DRD4HTR1ADRD2DRD3 | |
| SCHEMBL6360188 | 0.76 | DRD4 (0.84) | DRD4HTR1ADRD2DRD3 | |
| SCHEMBL6597096 | 0.76 | HTR1A (0.66) | DRD4HTR1ADRD2ALDH1A1MAPT | |
| SCHEMBL8120660 | 0.73 | DRD4 (0.58) | DRD4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6351475 | 0.73 | DRD4 (0.76) | DRD4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6351477 | 0.73 | DRD4 (0.76) | DRD4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9650843 | 0.72 | ADRA1D (1.00) | DRD4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3068873 | 0.72 | HTR1A (0.68) | DRD4HTR1ADRD2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |