Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592724 | 0.86 | BCL2 (0.62) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL792956 | 0.86 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL2891538 | 0.86 | PTPN1 (0.73) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL193474 | 0.86 | PTPN1 (0.73) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL193473 | 0.86 | PTPN1 (0.73) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL6161729 | 0.84 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL3350988 | 0.84 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL9752770 | 0.84 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL8094669 | 0.84 | CTSS (0.50) | ITGB3ITGA2BRENCTSSCTSK | |
| SCHEMBL3500186 | 0.84 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081132-B1 | HYDROXAMIC ACID DERIVATIVES AND MEDICINAL UTILIZATION THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6610729-B1 | Inhibotors of TNF, antiinflammatory | MITSUBISHI PHARMA CORPORATION (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1081132-A1 | HYDROXAMIC ACID DERIVATIVES AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-03-07 | — | — | EP | disclosed |