Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168840 | 0.86 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL13168837 | 0.83 | KMT2A (0.56) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7547799 | 0.77 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7825732 | 0.76 | TDP2 (0.31) | KMT2A | |
| SCHEMBL25786719 | 0.71 | NPSR1 (0.30) | — | |
| SCHEMBL19856524 | 0.71 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL19868510 | 0.71 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10516243 | 0.69 | CYP2D6 (0.45) | RAB9ASMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18123545 | 0.67 | KCNH2 (0.39) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL21098838 | 0.67 | MALT1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080090-B1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIV MADRID COMPLUTENSE (ES) | 2004-02-25 | — | — | EP | claimed |
| US-6525063-B2 | 3,7-dimethyl-1,5-diazaanthraquinone for example | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2003-02-25 | — | — | US | claimed |
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2002-07-25 | — | — | US | claimed |
| EP-1080090-B1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIV MADRID COMPLUTENSE (ES) | 2004-02-25 | — | — | EP | disclosed |
| US-6525063-B2 | 3,7-dimethyl-1,5-diazaanthraquinone for example | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2003-02-25 | — | — | US | disclosed |
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2002-07-25 | — | — | US | disclosed |
| EP-1080090-A1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999059996-A1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | PRMT7, TPD52L2, DRD4 | NPC1 3041/4885RAB9A 1345/4885SMN1; SMN2 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.