Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595249 | 0.85 | EGFR (0.43) | NPC1RAB9AKMT2AEGFREDNRA | |
| SCHEMBL7419460 | 0.84 | KMT2A (0.48) | MEN1KMT2AEGFRSRD5A2FLT3 | |
| SCHEMBL6595414 | 0.84 | ACHE (0.48) | NPC1RAB9AEGFRTDP1SCD | |
| SCHEMBL6176533 | 0.83 | S1PR1 (0.49) | — | |
| SCHEMBL7446077 | 0.83 | VNN1 (0.43) | KMT2AEGFRSRD5A2FLT3MAOB | |
| SCHEMBL7768225 | 0.78 | TDP1 (0.47) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7414778 | 0.78 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AEGFR | |
| SCHEMBL6171041 | 0.78 | ESR1 (0.61) | — | |
| SCHEMBL7774131 | 0.77 | HRH3 (0.43) | EGFR | |
| SCHEMBL6598084 | 0.77 | S1PR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980366-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |
| US-6271227-B1 | ANTICOAGULANTS | ELI LILLY AND COMPANY | 2001-08-07 | — | — | US | disclosed |