Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599562 | 0.85 | DUT (0.37) | TDP1DUTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6597552 | 0.84 | TDP1 (0.41) | TDP1ALDH1A1GAACYP3A4CYP2D6 | |
| SCHEMBL6599977 | 0.83 | TDP1 (0.42) | TDP1ALDH1A1GAACYP3A4CYP2D6 | |
| SCHEMBL6599980 | 0.81 | DUT (0.38) | DUTALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6598259 | 0.74 | CARM1 (0.36) | TDP1DUTIDO1KDM4ELMNA | |
| SCHEMBL6598215 | 0.73 | TDP1 (0.35) | TDP1ALDH1A1GAACYP3A4CYP2D6 | |
| SCHEMBL2830035 | 0.69 | DUT (0.39) | DUT | |
| SCHEMBL6599808 | 0.69 | MEN1 (0.40) | TDP1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8536947 | 0.66 | TAAR1 (0.41) | DUTIDO1 | |
| SCHEMBL21459252 | 0.64 | CNR1 (0.35) | ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |