Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114028 | 0.85 | ALOX15 (0.57) | ALOX15LMNAALDH1A1NPSR1HRH3 | |
| SCHEMBL14038235 | 0.85 | ALOX15 (0.55) | ALOX15LMNAALDH1A1NPSR1TSHR | |
| SCHEMBL3625293 | 0.77 | ALOX15 (0.38) | ALOX15LMNAALDH1A1NPSR1 | |
| SCHEMBL6594995 | 0.74 | ALDH1A1 (0.46) | ALOX15LMNAALDH1A1NPSR1CYP2C19 | |
| SCHEMBL13114031 | 0.73 | SMN1; SMN2 (0.46) | LMNAALDH1A1NPSR1HRH3CYP2C19 | |
| SCHEMBL13114037 | 0.72 | HTT (0.30) | ALOX15LMNAALDH1A1NPSR1 | |
| SCHEMBL4021051 | 0.72 | ALOX15 (0.44) | ALOX15LMNAALDH1A1NPSR1 | |
| SCHEMBL4026799 | 0.72 | NOTUM (0.37) | ALOX15LMNAALDH1A1NPSR1 | |
| SCHEMBL8654020 | 0.70 | ALOX15 (0.57) | ALOX15LMNAALDH1A1NPSR1TSHR | |
| SCHEMBL5399969 | 0.69 | HTT (0.39) | ALOX15LMNAALDH1A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1269813-C | Imidazolo-5-yl-2-anilino-pyrimidines as agents for inhibition of cell proliferation | ASTRAZENECA AB (SE) | 2006-08-16 | — | — | CN | disclosed |
| EP-1351958-B1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2004-06-16 | — | — | EP | disclosed |