SCHEMBL6598376

SCHEMBL6598376

CC(C)(C)c1csc(-c2cc3cc(Cn4nc5ccccc5c4C(=O)OCc4ccccc4)ccc3o2)n1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 19/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476880 0.87 PTGER4 (0.36) PTGER4
SCHEMBL6603445 0.86 CPT1A (0.38) PTGER4
SCHEMBL6601175 0.79 TSHR (0.33)
SCHEMBL8659965 0.79 MEN1 (0.40) PTGER4
SCHEMBL6598485 0.78 ALDH1A1 (0.39)
SCHEMBL6599969 0.77 SMN1; SMN2 (0.37)
SCHEMBL6600548 0.76 TP53 (0.31)
SCHEMBL6599253 0.76 F2RL3 (0.39)
SCHEMBL6600128 0.75 F2RL3 (0.37)
SCHEMBL6599836 0.74 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170009-B1 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO (JP) 2004-04-07 EP disclosed
EP-1170009-A2 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-09 EP disclosed
US-5994378-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed
EP-0880519-A1 THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-12-02 EP disclosed
WO-1997027190-A1 THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-07-31 WO disclosed