Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601175 | 0.81 | TSHR (0.33) | TP53TSHRSTAT1LMNA | |
| SCHEMBL6601208 | 0.80 | CCR2 (0.35) | — | |
| SCHEMBL7476880 | 0.80 | PTGER4 (0.36) | TP53TSHRSTAT1 | |
| SCHEMBL6600915 | 0.79 | PDE5A (0.34) | — | |
| SCHEMBL6600027 | 0.79 | PDE5A (0.34) | — | |
| SCHEMBL6600909 | 0.78 | PDE5A (0.34) | — | |
| SCHEMBL6597519 | 0.77 | — | — | |
| SCHEMBL6597036 | 0.76 | CNR1 (0.33) | — | |
| SCHEMBL6598376 | 0.76 | PTGER4 (0.39) | — | |
| SCHEMBL8659965 | 0.74 | MEN1 (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |