Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1194038 | 0.99 | LMNA (0.42) | LMNAKMT2APABPC1ATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL6609904 | 0.87 | POLB (0.34) | LMNAKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL6598021 | 0.86 | KMT2A (0.45) | LMNAKMT2APABPC1ATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL1193657 | 0.85 | KMT2A (0.44) | LMNAKMT2APABPC1ATMALDH1A1 | |
| SCHEMBL6598418 | 0.84 | KMT2A (0.36) | KMT2AKDM4ECYP2D6CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL5364641 | 0.83 | KMT2A (0.35) | KMT2AKDM4ECYP2D6MEN1HTT | |
| Bromide SCHEMBL1194131 | 0.83 | KMT2A (0.35) | KMT2AKDM4ECYP2D6CYP2C19MEN1 | |
| Bromide SCHEMBL6597813 | 0.82 | MAPT (0.34) | LMNAKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL6596014 | 0.75 | KMT2A (0.47) | LMNAKMT2APABPC1ATMALDH1A1 | |
| Bromide SCHEMBL1193597 | 0.74 | KMT2A (0.49) | LMNAKMT2APABPC1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |