Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18157879 | 0.88 | CALM1 (0.65) | CALM1CAMKK2ALDH1A1TSHRCARM1 | |
| SCHEMBL524817 | 0.88 | CALM1 (0.65) | CALM1CAMKK2ALDH1A1TSHRCARM1 | |
| SCHEMBL525423 | 0.82 | TSHR (0.56) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL16155087 | 0.81 | AOC3 (0.52) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL13962686 | 0.81 | CALM1 (0.58) | CALM1CAMKK2ALDH1A1TSHRCARM1 | |
| SCHEMBL21872330 | 0.81 | CALM1 (0.54) | CALM1CAMKK2ALDH1A1TSHRCARM1 | |
| SCHEMBL10039138 | 0.81 | TAAR1 (0.67) | CALM1CAMKK2ALDH1A1TSHRAOC3 | |
| SCHEMBL21872331 | 0.81 | CALM1 (0.54) | CALM1CAMKK2ALDH1A1TSHRCARM1 | |
| SCHEMBL10039137 | 0.80 | ALDH1A1 (0.58) | CALM1CAMKK2ALDH1A1TSHRCARM1 | |
| SCHEMBL10039144 | 0.79 | CALM1 (0.56) | CALM1CAMKK2ALDH1A1TSHRCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |