Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.65 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18157879 | 0.95 | CALM1 (0.65) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL10039144 | 0.90 | CALM1 (0.56) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL525423 | 0.90 | TSHR (0.56) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL10039141 | 0.89 | CALM1 (0.55) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL4821913 | 0.89 | CALM1 (0.55) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL4081568 | 0.88 | HTT (0.55) | CALM1CAMKK2ALDH1A1TSHRAOC3 | |
| SCHEMBL21872330 | 0.88 | CALM1 (0.54) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL21872331 | 0.88 | CALM1 (0.54) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL6598521 | 0.88 | CALM1 (0.54) | CALM1CAMKK2ALDH1A1TSHRTAAR1 | |
| SCHEMBL13962686 | 0.88 | CALM1 (0.58) | CALM1CAMKK2ALDH1A1TSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104086511-B | Double-reaction-active-group double-cationic-group cation modifier, and preparation method and application thereof | 广东溢达纺织有限公司 | 2017-02-15 | — | — | CN | disclosed |
| EP-2598111-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | UNILEVER PLC (GB) | 2015-03-25 | — | — | EP | disclosed |
| EP-2598111-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | UNILEVER PLC (GB) | 2015-03-25 | — | — | EP | disclosed |
| CN-104086511-A | Double-reaction-active-group double-cationic-group cation modifier, and preparation method and application thereof | GUANGDONG ESQUEL TEXTILES CO | 2014-10-08 | — | — | CN | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CUTA, TYR, DSG1 | CALM1 3930/4885CAMKK2 4844/4885ALDH1A1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.