Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | ICMT | O60725 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610414 | 0.95 | PPARD (0.39) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL6598709 | 0.90 | THRA (0.44) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL6598794 | 0.88 | PLA2G2A (0.47) | PLA2G2APPARDPPARGPPARATHRA | |
| Acetic Acid SCHEMBL6598580 | 0.86 | S1PR1 (0.40) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL5810585 | 0.85 | PLA2G2A (0.41) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL6601718 | 0.85 | PLA2G2A (0.38) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL5809194 | 0.84 | THRA (0.41) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL8624729 | 0.84 | THRA (0.46) | PLA2G2APPARDPPARGPPARATHRA | |
| SCHEMBL6601187 | 0.84 | PLA2G2A (0.49) | PLA2G2APPARDPPARGPPARAICMT | |
| SCHEMBL6599665 | 0.84 | PLA2G2A (0.39) | PLA2G2APPARDPPARGPPARAICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |