Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | ICMT | O60725 | 4/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809194 | 0.94 | THRA (0.41) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL6598709 | 0.94 | THRA (0.44) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL6601187 | 0.92 | PLA2G2A (0.49) | PPARDPPARGPPARAPLA2G2AICMT | |
| SCHEMBL5810419 | 0.92 | PPARD (0.53) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL6599833 | 0.91 | PLA2G2A (0.47) | THRATHRBPPARDPPARGPPARA | |
| Acetic Acid SCHEMBL6610409 | 0.90 | S1PR1 (0.42) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL7479941 | 0.89 | PPARD (0.43) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL6610414 | 0.89 | PPARD (0.39) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL6599124 | 0.88 | PLA2G2A (0.42) | THRATHRBPPARDPPARGPPARA | |
| SCHEMBL6598614 | 0.88 | PPARD (0.48) | PPARDPPARGPPARAPLA2G2AICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |