SCHEMBL659868

SCHEMBL659868

CCCCCC(C)(C)c1cccc(C(=O)O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
ALB P02768 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
MMP2 P08253 1/20 0.40
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
TSHR P16473 1/20 0.39
HMGB1 P09429 1/20 0.39
KAT8 Q9H7Z6 4/20 0.38
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
PPARA Q07869 2/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3010386 0.99 ALDH1A1 (0.42) KDM4EALBALDH1A1HPGDHSD17B10
SCHEMBL9795331 0.97 ALDH1A1 (0.41) KDM4EALBALDH1A1HPGDHSD17B10
SCHEMBL9795325 0.85 CNR1 (0.40) ALDH1A1CNR1CNR2TSHRMEN1
Zinc Ion SCHEMBL9299896 0.85 CNR1 (0.40) ALDH1A1CNR1CNR2TSHRMEN1
SCHEMBL1833406 0.84 CA2 (0.48) CNR1CNR2
SCHEMBL8906262 0.84 BID (0.43) KDM4EALDH1A1HSD17B10CA12CA9
SCHEMBL3831753 0.83 ALDH1A1 (0.50) KDM4EALBALDH1A1HPGDHSD17B10
SCHEMBL17148818 0.82 CNR2 (0.49) CNR1CNR2
SCHEMBL1839805 0.82 CNR2 (0.49) CNR1CNR2
SCHEMBL1839224 0.82 CNR2 (0.49) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110741237-A Material for pressure measurement 富士胶片株式会社 2020-01-31 CN disclosed
US-8507182-B2 Method of providing lithographic printing plates EASTMAN KODAK COMPANY (US) 2013-08-13 US disclosed
US-8420297-B2 Developers and method of coloring lithographic printing members EASTMAN KODAK COMPANY (US) 2013-04-16 US disclosed
US-8247163-B2 Preparing lithographic printing plates with enhanced contrast EASTMAN KODAK COMPANY (US) 2012-08-21 US disclosed
US-8240943-B2 On-press developable imageable elements EASTMAN KODAK COMPANY (US) 2012-08-14 US disclosed
EP-2297611-B1 ON-PRESS DEVELOPABLE IMAGEABLE ELEMENTS EASTMAN KODAK CO (US) 2012-07-11 EP disclosed
EP-2440978-A1 PREPARING LITHOGRAPHC PRINTING PLATES WITH ENHANCED CONTRAST Eastman Kodak Company (US) 2012-04-18 EP disclosed
EP-2288507-B1 SUBSTRATE AND IMAGEABLE ELEMENT WITH HYDROPHILIC INTERLAYER EASTMAN KODAK CO (US) 2012-02-29 EP disclosed
US-20120045720-A1 DEVELOPERS AND METHOD OF COLORING LITHOGRAPHIC PRINTING MEMBERS KODAK REALTY INC. 2012-02-23 US disclosed
US-8084182-B2 On-press developable elements and methods of use EASTMAN KODAK COMPANY (US) 2011-12-27 US disclosed
EP-0242863-A2 Process for manufacturing lithographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 1987-10-28 EP disclosed
EP-0242864-A2 A process for making a lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1987-10-28 EP disclosed
US-4682194-A MICROCAPSULES CONTAINING LEUCO DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
EP-0109838-B1 LIGHT AND HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-04-08 EP disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed
US-4598035-A LEUCO AND DISAZO DYES FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US disclosed
US-4533929-A ANIONIC SURFACTANTS AS ANTIFOGGING AGENTS; DIETHYLHEXYL SULFOSUCCINATE FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US disclosed
US-4529681-A Microcapsules containing vinyl compound, photoinitiator and color forming compound FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
US-4479138-A PHENYL BENZOIC ESTER TO INCREASE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045720-A1 DEVELOPERS AND METHOD OF COLORING LITHOGRAPHIC PRINTING MEMBERS ALG3, COG7, ALG1 KDM4E 3679/4885ALB 2384/4885ALDH1A1 1241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.