SCHEMBL6599258

SCHEMBL6599258

FC1(F)Oc2ccc(CBr)cc2C(F)(F)O1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.45
GCGR P47871 1/20 0.33
GIPR P48546 1/20 0.33
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9071123 0.85 KIF11 (0.44) KIF11GCGRGIPR
SCHEMBL1721979 0.85 KIF11 (0.44) KIF11GCGRGIPR
SCHEMBL1723713 0.85 KIF11 (0.44) KIF11GCGRGIPRCYP19A1
SCHEMBL1721735 0.81 KIF11 (0.41) KIF11
SCHEMBL1722673 0.79 KIF11 (0.47) KIF11
SCHEMBL2537768 0.76 CYP19A1 (0.43) KIF11CYP19A1
SCHEMBL423133 0.75 KIF11 (0.47) KIF11
SCHEMBL3612411 0.75 KIF11 (0.50) KIF11
SCHEMBL19563466 0.71 KIF11 (0.53) KIF11GCGRGIPR
SCHEMBL2560230 0.71 KIF11 (0.44) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040152903-A1 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides KUREHA CORPORATION (JP) 2004-08-05 US disclosed
EP-1375483-A1 6-CHLORO-3-PYRIDYLMETHYLPROPYLAMINE DERIVATIVES, PREPARATION PROCESS THEREOF AND BACTERICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152903-A1 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides PGLS, TLR6, UROD KIF11 3647/4885GCGR 4312/4885GIPR 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.