SCHEMBL6599296

SCHEMBL6599296

CC(C)Cc1ccc(-c2cc[c]cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
PTGS1 P23219 4/20 0.41
PTGS2 P35354 4/20 0.41
LMNA P02545 2/20 0.41
CYP2C9 P11712 2/20 0.41
AKR1C3 P42330 2/20 0.41
CXCR1 P25024 2/20 0.41
CXCR2 P25025 2/20 0.41
AKR1C2 P52895 2/20 0.41
ALB P02768 1/20 0.41
ESR1 P03372 1/20 0.41
ALOX5 P09917 1/20 0.41
RARB P10826 1/20 0.41
ADRB3 P13945 1/20 0.41
NFKB1 P19838 1/20 0.41
HTR2A P28223 1/20 0.41
NR1I3 Q14994 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59521 0.86 PTGS1 (0.42) MEN1POLBMAPTKMT2APTGS1
Water SCHEMBL27361343 0.86 PTGS1 (0.42) MEN1POLBMAPTKMT2APTGS1
SCHEMBL8636154 0.86 MEN1 (0.53) MEN1POLBMAPTKMT2APTGS1
SCHEMBL27360231 0.84 PTGS1 (0.41) MEN1POLBMAPTKMT2APTGS1
SCHEMBL27399339 0.84 PTGS1 (0.41) MEN1POLBMAPTKMT2APTGS1
SCHEMBL28099383 0.84 PTGS1 (0.41) MEN1POLBMAPTKMT2APTGS1
SCHEMBL27301228 0.83 TAAR1 (0.53)
SCHEMBL9864763 0.83 GPR84 (0.42) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL10338370 0.82 BDKRB2 (0.35) MEN1POLBMAPTKMT2AESR1
SCHEMBL10338368 0.82 BDKRB2 (0.35) MEN1POLBMAPTKMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926175-A Halogen-free polyphosphate flame retardant with high polymerization degree and preparation method thereof 缔久高科技材料(南通)有限公司 2023-04-07 CN claimed
EP-4291592-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP America Inc. (US) 2023-12-20 EP disclosed
CN-110997689-B Aminoglycoside derivatives and their use in the treatment of genetic disorders ELOXX制药有限公司 2023-11-07 CN disclosed
CN-115926175-A Halogen-free polyphosphate flame retardant with high polymerization degree and preparation method thereof 缔久高科技材料(南通)有限公司 2023-04-07 CN disclosed
WO-2022173532-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2022-08-18 WO disclosed
EP-3606971-B1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2022-01-12 EP disclosed
US-20200181359-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2020-06-11 US disclosed
EP-3645297-A1 IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2020-05-06 EP disclosed
US-10597511-B2 Reactive flame retardant blends for flexible polyurethane foam ICL-IP AMERICA INC. (US) 2020-03-24 US disclosed
EP-3606971-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP America Inc. (US) 2020-02-12 EP disclosed
WO-2019060035-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2019-03-28 WO disclosed
US-20190085151-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP AMERICA INC. 2019-03-21 US disclosed
CN-107082788-A It is a kind of that the synthetic method that P (O) OH classes compound is efficiently esterified with alcohol is catalyzed with imines 湖南理工学院 2017-08-22 CN disclosed
EP-1385833-A1 TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS Amgen Inc. (US) 2004-02-04 EP disclosed
WO-2002083654-A1 TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS AMGEN INC. (US) 2002-10-24 WO disclosed
EP-0821675-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-02-04 EP disclosed
WO-1996033176-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-10-24 WO disclosed