Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38095 | 0.74 | IDH1 (0.35) | — | |
| SCHEMBL38109 | 0.72 | — | — | |
| SCHEMBL2794616 | 0.72 | KMT2A (0.33) | KDM4EABL1LMNAKMT2ARECQL | |
| SCHEMBL2744014 | 0.71 | AR (0.40) | KMT2A | |
| SCHEMBL37681 | 0.70 | CNR2 (0.43) | KMT2A | |
| SCHEMBL30697766 | 0.69 | MAPT (0.48) | LMNAKMT2ARECQL | |
| SCHEMBL2794658 | 0.68 | PIK3CA (0.32) | — | |
| SCHEMBL2791478 | 0.67 | SYK (0.33) | KDM4EABL1LMNARECQL | |
| SCHEMBL8235167 | 0.64 | TDO2 (0.40) | KDM4E | |
| SCHEMBL4779033 | 0.64 | SYK (0.36) | KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | Warner-Lambert Company LLC (US) | 2004-10-13 | — | — | EP | claimed |
| WO-2003045912-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2003-06-05 | — | — | WO | claimed |