Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 3/20 | 0.31 |
| ▸ | RXRG | P48443 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38109 | 0.83 | — | — | |
| SCHEMBL15553072 | 0.76 | CRBN (0.49) | — | |
| SCHEMBL46307 | 0.75 | GPR119 (0.41) | IDH1RXRARXRBRXRG | |
| SCHEMBL16498267 | 0.74 | GRIN2D (0.38) | IDH1 | |
| SCHEMBL6599307 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL8194170 | 0.73 | MAPT (0.48) | — | |
| SCHEMBL37681 | 0.71 | CNR2 (0.43) | IDH1 | |
| SCHEMBL8235167 | 0.71 | TDO2 (0.40) | IDH1 | |
| SCHEMBL15416403 | 0.71 | IDH1 (0.36) | IDH1PIK3CD | |
| SCHEMBL16699036 | 0.70 | DDB1 (0.36) | IDH1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |