Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 7/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825466 | 0.72 | KMT2A (0.49) | HTTSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL22289540 | 0.72 | NOS3 (0.48) | NOS3NOS1NOS2TNFKDM4E | |
| SCHEMBL3621544 | 0.72 | PPARA (0.57) | SLC1A5NOS3NOS1NOS2PPARA | |
| SCHEMBL22289541 | 0.72 | NOS3 (0.48) | NOS3NOS1NOS2TNFKDM4E | |
| Methyl Alcohol SCHEMBL28880032 | 0.72 | NOS3 (0.56) | SLC1A5NOS3NOS1NOS2PPARA | |
| SCHEMBL298903 | 0.72 | PKM (0.58) | SLC1A5NOS3NOS1NOS2PPARA | |
| SCHEMBL43976 | 0.72 | PKM (0.58) | SLC1A5NOS3NOS1NOS2PPARA | |
| SCHEMBL35491891 | 0.72 | PKM (0.58) | SLC1A5NOS3NOS1NOS2PPARA | |
| SCHEMBL29351556 | 0.72 | PKM (0.58) | SLC1A5NOS3NOS1NOS2PPARA | |
| SCHEMBL43977 | 0.72 | PKM (0.58) | SLC1A5NOS3NOS1NOS2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448532-A1 | 5-PHENYLPYRIMIDINES, AGENTS COMPRISING THE SAME, METHOD FOR PRODUCTION AND USE THEREOF | BASF Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003043993-A1 | 5-PHENYLPYRIMIDINES, AGENTS COMPRISING THE SAME, METHOD FOR PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |