Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6594709 | 0.99 | HTR1A (0.69) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL8120660 | 0.85 | DRD4 (0.58) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL9650932 | 0.84 | ADRA1A (0.70) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9652267 | 0.82 | ADRA1D (0.81) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9653903 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1MAPTHTTKMT2APOLB | |
| SCHEMBL6352028 | 0.80 | HTR1A (1.00) | HTR1AALDH1A1MAPTHTTKMT2A | |
| Hydrochloric Acid SCHEMBL6599492 | 0.79 | HTR1A (0.66) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL6596142 | 0.79 | HTR1A (1.00) | HTR1AALDH1A1MAPTHTTKMT2A | |
| Benzene SCHEMBL10433203 | 0.79 | HTR1A (0.79) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL3160665 | 0.79 | HTR1A (0.79) | HTR1AALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |