Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080317 | 0.91 | MEN1 (0.39) | MRGPRX4LTB4RLTB4R2PTGER1RPS6KB1 | |
| SCHEMBL6081085 | 0.91 | NOTUM (0.41) | MRGPRX4LTB4RLTB4R2RPS6KB1 | |
| SCHEMBL6592207 | 0.90 | MRGPRX4 (0.44) | MRGPRX4LTB4RLTB4R2PTGER1ALOX15 | |
| SCHEMBL6602356 | 0.87 | MRGPRX4 (0.42) | MRGPRX4LTB4RLTB4R2PTGER1ALOX15 | |
| SCHEMBL6672382 | 0.83 | PTGER1 (0.43) | MRGPRX4PTGER1MCL1 | |
| Hydrochloric Acid SCHEMBL6080861 | 0.82 | RPS6KB1 (0.41) | ALOX15RPS6KB1 | |
| SCHEMBL6672379 | 0.81 | ALOX15 (0.40) | MRGPRX4PTGER1ALOX15PPARA | |
| SCHEMBL6080646 | 0.80 | NOTUM (0.42) | MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL6081092 | 0.80 | LTB4R (0.41) | LTB4RLTB4R2PTGER1RPS6KB1PPARA | |
| SCHEMBL6590520 | 0.79 | MRGPRX4 (0.47) | MRGPRX4PTGER1MCL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |