Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602356 | 0.85 | MRGPRX4 (0.42) | ALOX15MRGPRX4PTGER1 | |
| SCHEMBL6592207 | 0.84 | MRGPRX4 (0.44) | ALOX15MRGPRX4PTGER1 | |
| SCHEMBL6599537 | 0.81 | MRGPRX4 (0.42) | ALOX15MRGPRX4PTGER1PPARA | |
| SCHEMBL6672382 | 0.78 | PTGER1 (0.43) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL6079313 | 0.77 | NOTUM (0.41) | MRGPRX4 | |
| SCHEMBL6590520 | 0.76 | MRGPRX4 (0.47) | MRGPRX4PTGER1CYP1A2 | |
| SCHEMBL6596767 | 0.76 | MRGPRX4 (0.47) | ALOX15MRGPRX4PTGER1 | |
| SCHEMBL6598155 | 0.75 | PTGER1 (0.50) | RXRARXRBRXRGMRGPRX4PTGER1 | |
| SCHEMBL6080646 | 0.75 | NOTUM (0.42) | MRGPRX4 | |
| SCHEMBL2908552 | 0.73 | ALOX15 (0.64) | ALOX15MRGPRX4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |