Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699235 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1TSHRTDP1 | |
| SCHEMBL20838472 | 0.83 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1TSHRLMNA | |
| SCHEMBL6594784 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1TSHRTDP1 | |
| SCHEMBL6537694 | 0.77 | KMT2A (0.55) | ALDH1A1MAPTL3MBTL1TSHRTDP1 | |
| SCHEMBL1562891 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1TSHRTDP1 | |
| SCHEMBL461099 | 0.76 | MAPT (0.69) | ALDH1A1MAPTL3MBTL1TSHRLMNA | |
| SCHEMBL9069976 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1TSHRTDP1 | |
| SCHEMBL10005935 | 0.74 | MAPT (0.72) | MAPTL3MBTL1TSHRLMNACRHR1 | |
| SCHEMBL1625586 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTTSHRTDP1LMNA | |
| SCHEMBL563664 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTTSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |