Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16766999 | 0.88 | LMNA (0.36) | LMNAMEN1KMT2A | |
| SCHEMBL28424050 | 0.82 | IDO1 (0.36) | LMNAMEN1KMT2A | |
| SCHEMBL1926319 | 0.77 | METAP2 (0.50) | LMNAMEN1KMT2A | |
| SCHEMBL989177 | 0.77 | CA12 (0.42) | MEN1KMT2A | |
| SCHEMBL1260621 | 0.77 | LMNA (0.32) | LMNAMEN1KMT2A | |
| SCHEMBL3442252 | 0.77 | METAP2 (0.50) | LMNAMEN1KMT2A | |
| SCHEMBL2765284 | 0.77 | KMT2A (0.52) | LMNAMEN1KMT2A | |
| SCHEMBL9955 | 0.77 | METAP2 (0.50) | LMNAMEN1KMT2A | |
| SCHEMBL1645103 | 0.77 | METAP2 (0.50) | MEN1KMT2A | |
| SCHEMBL8486152 | 0.77 | LMNA (0.35) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385833-A1 | TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | Amgen Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083654-A1 | TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AMGEN INC. (US) | 2002-10-24 | — | — | WO | disclosed |