Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 3/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10565482 | 0.98 | METAP2 (0.48) | METAP2NOTUMALPLHAO1CA12 | |
| Methylamine SCHEMBL27885520 | 0.94 | METAP2 (0.46) | METAP2NOTUMALPLHAO1CA12 | |
| SCHEMBL28822256 | 0.90 | LTA4H (0.51) | METAP2NOTUMHAO1MAPTNPSR1 | |
| SCHEMBL16766999 | 0.88 | LMNA (0.36) | METAP2NOTUMMAPTMEN1NPC1 | |
| SCHEMBL8431079 | 0.80 | IDO1 (0.35) | METAP2NOTUM | |
| SCHEMBL23657490 | 0.78 | SMN1; SMN2 (0.42) | METAP2NOTUMHAO1MAPTLTA4H | |
| SCHEMBL1926319 | 0.77 | METAP2 (0.50) | METAP2ALPLMAPTMEN1NPC1 | |
| SCHEMBL8486152 | 0.77 | LMNA (0.35) | MEN1KMT2A | |
| SCHEMBL3442252 | 0.77 | METAP2 (0.50) | METAP2ALPLMAPTMEN1NPC1 | |
| SCHEMBL9955 | 0.77 | METAP2 (0.50) | METAP2MAPTNPSR1LTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393416-B | Preparation method and application of pyrazole compound containing 1-methylpyridine-3- (4-chlorphenyl) pyrazole unit | 南通大学 | 2022-08-12 | — | — | CN | claimed |
| CN-102056903-A | New drug for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases | UNIV MUENCHEN L MAXIMILIANS | 2011-05-11 | — | — | CN | claimed |
| EP-4595753-A1 | PHENYLPYRAZOLE COMPOUND, AND PLANT DISEASE CONTROL METHOD | Sumitomo Chemical Company, Limited (JP) | 2025-08-06 | — | — | EP | disclosed |
| CN-119947587-A | Phenylpyrazole compound and method for controlling plant disease | 住友化学株式会社 | 2025-05-06 | — | — | CN | disclosed |
| US-12225904-B2 | Phenylpyrazole compound and method for controlling plant disease | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-02-18 | — | — | US | disclosed |
| WO-2024071395-A1 | PHENYLPYRAZOLE COMPOUND, AND PLANT DISEASE CONTROL METHOD | 住友化学株式会社 | 2024-04-04 | — | — | WO | disclosed |
| EP-3959200-B1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | ANADOLU UNIV (TR) | 2024-03-20 | — | — | EP | disclosed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| CN-111741956-B | Antiparasitic depsipeptides | 硕腾服务有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-112839505-B | Phenylpyrazole compound and method for controlling plant disease | 住友化学株式会社 | 2023-06-06 | — | — | CN | disclosed |
| CN-110483400-B | Preparation method of pyrazole derivative | 上海应用技术大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-1235514-A | Herbicides based on 4-bromo-1-methyl-5-trifluoromethyl-3- (2-fluoro-4-chloro-5-isopropoxycarbonylphenyl) pyrazole | BAYER AG (DE) | 1999-11-17 | — | — | CN | disclosed |
| US-5945382-A | AND A METHOD OF THEIR PREPARATION BY CHLORINATION OF AN INTERMEDIATE ARYLPYRAZOLE; PROTECTION AGAINST FUNGAL DISEASES IN TOMATO, RICE, AND WHEAT PLANTS | RHONE-POULENC AGROCHIMIE (FR) | 1999-08-31 | — | — | US | disclosed |
| EP-0923288-A1 | HERBICIDES BASED ON 4-BROMO-1-METHYL-5-TRIFLUOROMETHYL-3-(2-FLUORO-4-CHLORO-5-ISOPROPOXYCARBONYLPHENYL)PYRAZOLE | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008383-A1 | HERBICIDES BASED ON 4-BROMO-1-METHYL-5-TRIFLUOROMETHYL-3-(2-FLUORO-4-CHLORO-5-ISOPROPOXYCARBONYLPHENYL)PYRAZOLE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-05 | — | — | WO | disclosed |
| EP-0638070-A1 | FUNGICIDAL ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993022287-A1 | FUNGICIDAL ARYLPYRAZOLES | RHONE POULENC AGROCHIMIE (FR) | 1993-11-11 | — | — | WO | disclosed |
| US-4833136-A | ANTIINFLAMMATORY AGENTS | BEECHAM GROUP P.L.C. (GB) | 1989-05-23 | — | — | US | disclosed |
| EP-0239191-A2 | Pyrazolo[4,3-b]pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-30 | — | — | EP | disclosed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12225904-B2 | Phenylpyrazole compound and method for controlling plant disease | HRH3, H1-3, HRH4 | METAP2 3497/4885NOTUM 476/4885ALPL 3328/4885 |
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | METAP2 250/4885NOTUM 3584/4885ALPL 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.