⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447749 | 0.98 | DAO (0.40) | — | |
| SCHEMBL2403742 | 0.70 | — | — | |
| SCHEMBL1538831 | 0.70 | — | — | |
| SCHEMBL436505 | 0.70 | — | — | |
| SCHEMBL29951334 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL29957364 | 0.70 | MAPK14 (0.31) | — | |
| SCHEMBL28348831 | 0.70 | DAO (0.47) | — | |
| SCHEMBL12584575 | 0.70 | ENPP2 (0.44) | — | |
| SCHEMBL14492465 | 0.66 | PRMT6 (0.34) | — | |
| SCHEMBL29954639 | 0.66 | ENPP2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303150-A | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2020-06-19 | — | — | CN | claimed |
| US-20260055114-A1 | IMIDAZO[1,2-B]PYRIDAZINE INHIBITORS OF CYCLIN-DEPENDENT KINASES | H LEE MOFFITT CANCER CT & RES (US) | 2026-02-26 | — | — | US | disclosed |
| US-20240018103-A1 | 3-HYDROXYOXINDOLE DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| EP-4277892-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2023-11-22 | — | — | EP | disclosed |
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2022152705-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2022-07-21 | — | — | WO | disclosed |
| CN-112851701-B | Anthracene-based mechanoluminescence organic material and preparation method and application thereof | 吉林大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-111303150-B | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2021-10-19 | — | — | CN | disclosed |
| EP-3668880-B1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-10-06 | — | — | EP | disclosed |
| WO-2009074234-A1 | NOVEL 2-SUBSTITUTED THIAZOLE-4-CARBOXAMIDE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | disclosed |
| EP-2070925-A1 | New 2-substituted tiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
| EP-2070925-A1 | New 2-substituted tiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
| US-20090149517-A1 | NOVEL 2-SUBSTITUTED TIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149517-A1 | NOVEL 2-SUBSTITUTED TIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149517-A1 | NOVEL 2-SUBSTITUTED TIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090118522-A1 | Synthesis of Cyclopentadienedithiophene Derivatives | BASELL POLYOLEFINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-1926738-A1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | Basell Polyolefine GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| US-20070232632-A1 | Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| WO-2007033937-A1 | SYNTHESIS OF CYCLOPENTADIENEDITHIOPHENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2007-03-29 | — | — | WO | disclosed |