Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 6/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TDO2 | P48775 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690382 | 0.84 | PTGS2 (0.50) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL6286367 | 0.82 | PTGS2 (0.48) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL6286370 | 0.81 | MEN1 (0.50) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL6505966 | 0.81 | PTGS2 (0.50) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL6605134 | 0.80 | MAPK14 (0.53) | PTGS2MAPK14CDC7DBF4IDO1 | |
| SCHEMBL6279375 | 0.79 | PTGS2 (0.54) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL6280962 | 0.79 | PTGS2 (0.48) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL6503233 | 0.79 | PTGS2 (0.78) | PTGS2MAPK14 | |
| SCHEMBL6502554 | 0.79 | PTGS2 (0.51) | PTGS2KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL15688673 | 0.79 | PTGS2 (0.65) | PTGS2MAPK14CDC7DBF4CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402900-A1 | MEDICINAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |