SCHEMBL660089

SCHEMBL660089

Cc1cc(C)c(N=C=S)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
RAPGEF4 Q8WZA2 3/20 0.35
MIF P14174 1/20 0.32
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390818 0.85 RAPGEF4 (0.33) GABRA1GABRB2RAPGEF4
SCHEMBL1547925 0.83 MIF (0.41) GABRA1GABRB2MIFALDH1A1LMNA
SCHEMBL11414739 0.82 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL11429392 0.82 SMN1; SMN2 (0.41) GABRA1GABRB2ALDH1A1
SCHEMBL11429373 0.82 GABRA1 (0.52) GABRA1GABRB2ALDH1A1LMNA
SCHEMBL1457241 0.81 GABRA1 (0.36) GABRA1GABRB2MIF
SCHEMBL8957812 0.81 GABRA1 (0.36) GABRA1GABRB2MIFALDH1A1
SCHEMBL14102097 0.81 MEN1 (0.47) GABRA1GABRB2MIFALDH1A1GAA
SCHEMBL961129 0.79 RAPGEF4 (0.38) RAPGEF4ALDH1A1LMNAKDM4EGAA
SCHEMBL26941830 0.79 FFAR1 (0.31) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-12232516-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-02-25 US claimed
US-12193465-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-01-14 US claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
US-20220264914-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-08-25 US claimed
US-20220225647-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
US-20220225646-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
EP-3221309-B1 NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS COUNCIL SCIENT IND RES (IN) 2019-11-13 EP claimed
EP-3253750-B1 NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2019-04-10 EP claimed
US-10221165-B2 Flavone based EGFR inhibitors and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2019-03-05 US claimed
US-20180016268-A1 Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-01-18 US claimed
US-9862712-B2 Benzimidazole based EGFR inhibitors COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-01-09 US claimed
EP-3221309-A1 NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS Council of Scientific and Industrial Research (IN) 2017-09-27 EP claimed
US-20170267671-A1 NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-09-21 US claimed
WO-2016079763-A1 NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-05-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267671-A1 NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS EGFR, ERBB4, ERBB2 GABRA1 1933/4885GABRB2 1253/4885RAPGEF4 3046/4885
US-20180016268-A1 Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof EGFR, ERBB2, ABL1 GABRA1 3129/4885GABRB2 3415/4885RAPGEF4 1358/4885
US-10221165-B2 Flavone based EGFR inhibitors and process for preparation thereof EGFR, ERBB2, ABL1 GABRA1 3100/4885GABRB2 3429/4885RAPGEF4 1539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.