SCHEMBL961129

SCHEMBL961129

Cc1cc(C)c(N=C=Nc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.38
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16353486 0.89 TRPA1 (0.34) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL11428515 0.84 RAPGEF4 (0.34) RAPGEF4ALDH1A1LMNAMAPTKMT2A
SCHEMBL11420509 0.80 TRPA1 (0.31) LMNA
SCHEMBL660089 0.79 GABRA1 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL1192169 0.79 CYP3A4 (0.42) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8829139 0.79 RAPGEF4 (0.35) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL362146 0.74 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL3286343 0.73 MEN1 (0.48) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL502928 0.73 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL3286340 0.73 MEN1 (0.48) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134947-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US claimed
WO-2016159817-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER CANADA LIMITED (CA) 2016-10-06 WO claimed
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-02-24 US disclosed
US-20240294748-A1 FILM COMPRISING POLYLACTIC ACID POLYMER SUITABLE FOR GRAPHIC ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-09-05 US disclosed
US-12065531-B2 Polyglycolic acid resin and production process thereof PUJING CHEMICAL INDUSTRY CO., LTD. (CN) 2024-08-20 US disclosed
EP-4400527-A1 SEMI-AROMATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400530-A1 POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-4400529-A1 SEMI-AROMATIC POLYETHER ESTER, PREPARATION METHOD THEREFOR AND USE THEREOF Zhuhai Wango Chemical Co., Ltd. (CN) 2024-07-17 EP disclosed
WO-2024111181-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT ポリプラ・エボニック株式会社 2024-05-30 WO disclosed
CN-111944278-B Liquid crystalline polymer composition 上野制药株式会社 2024-05-28 CN disclosed
WO-2024101133-A1 FLAME RETARDANT POLYESTER ELASTOMER RESIN COMPOSITION 東洋紡エムシー株式会社 2024-05-16 WO disclosed
EP-1846426-A1 TRANSITION METAL POLYMERIZATION CATALYSTS, THEIR SYNTHESIS AND USE IN OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-10-24 EP disclosed
US-7268190-B2 Resin composition comprising polylactic acid and polyacetal and a molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2007-09-11 US disclosed
EP-1792941-A1 RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2007-06-06 EP disclosed
US-20060276617-A1 Aliphatic polyester resin composition, preparation method therefor, and molded article and foamed article produced from the resin composition UNITIKA LTD. (JP) 2006-12-07 US disclosed
WO-2006083549-A1 TRANSITION METAL POLYMERIZATION CATALYSTS, THEIR SYNTHESIS AND USE IN OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-08-10 WO disclosed
US-20060173144-A1 Transition metal polymerization catalysts, their synthesis and use in olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-03 US disclosed
EP-1640406-A1 ALIPHATIC POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCTION THEREOF, MOLDED ARTICLE AND FOAMED ARTICLE COMPRISING THE RESIN COMPOSITION UNITIKA LTD. (JP) 2006-03-29 EP disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065531-B2 Polyglycolic acid resin and production process thereof RPN2, RIOX2, RPN1 RAPGEF4 3396/4885ALDH1A1 3675/4885KDM4E 2258/4885
US-20060173144-A1 Transition metal polymerization catalysts, their synthesis and use in olefin polymerization SOD1, CCNT1, MYB RAPGEF4 1879/4885ALDH1A1 2080/4885KDM4E 3640/4885
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles POT1, PARG, TCP1 RAPGEF4 2359/4885ALDH1A1 373/4885KDM4E 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.