Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 4/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | FCER2 | P06734 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601730 | 0.97 | ZAP70 (0.34) | CAPN1ZAP70SRCFCER2GHSR | |
| SCHEMBL6601080 | 0.91 | SMN1; SMN2 (0.38) | CAPN1FCER2CTSLCTSBPRSS1 | |
| SCHEMBL3728180 | 0.89 | SLC7A11 (0.35) | CAPN1ZAP70SRCFCER2GHSR | |
| SCHEMBL6601402 | 0.89 | CAPN1 (0.39) | CAPN1ZAP70SRCFCER2GHSR | |
| SCHEMBL4282444 | 0.89 | CAPN1 (0.39) | CAPN1ZAP70SRCFCER2GHSR | |
| SCHEMBL6600536 | 0.87 | SLC7A11 (0.34) | FCER2GHSRSLC7A11 | |
| SCHEMBL8579396 | 0.80 | SMN1; SMN2 (0.41) | CAPN1ZAP70SRCFCER2GHSR | |
| SCHEMBL6602122 | 0.78 | MC4R (0.42) | ZAP70SRCFCER2GHSRSLC7A11 | |
| SCHEMBL4284133 | 0.78 | MAOB (0.37) | CAPN1ZAP70SRCGHSRSLC7A11 | |
| SCHEMBL6601217 | 0.78 | PSMB5 (0.36) | FCER2GHSRSLC7A11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |