Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601402 | 0.91 | CAPN1 (0.39) | GHSRCAPN1FCER2MAOBPSMB5 | |
| SCHEMBL4282444 | 0.91 | CAPN1 (0.39) | GHSRCAPN1FCER2MAOBPSMB5 | |
| SCHEMBL6601080 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP1A2CYP2D6CYP2C19BMP1 | |
| SCHEMBL4284133 | 0.88 | MAOB (0.37) | SMN1; SMN2BMP1GHSRCAPN1MAOB | |
| SCHEMBL8579403 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP1A2CYP2D6CYP2C19BMP1 | |
| SCHEMBL6601083 | 0.84 | MC4R (0.41) | SMN1; SMN2CYP1A2CYP2D6CYP2C19BMP1 | |
| SCHEMBL6601217 | 0.84 | PSMB5 (0.36) | GHSRFCER2MAOBPSMB5 | |
| SCHEMBL6606297 | 0.81 | PSMB5 (0.37) | GHSRMAOBPSMB5 | |
| SCHEMBL6600950 | 0.80 | CAPN1 (0.37) | GHSRCAPN1FCER2PRSS1PRSS2 | |
| SCHEMBL6600377 | 0.79 | CTSS (0.50) | FCER2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907374-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997046252-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1997-12-11 | — | — | WO | disclosed |