Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.35 |
| ▸ | FCER2 | P06734 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600950 | 0.91 | CAPN1 (0.37) | PRSS1PRSS2PRSS3TPSAB1CAPN1 | |
| SCHEMBL8579396 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2BMP1NR1H4CYP1A2CYP2D6 | |
| SCHEMBL6601730 | 0.87 | ZAP70 (0.34) | ALDH1A1CAPN1FCER2RAB9A | |
| SCHEMBL3728180 | 0.86 | SLC7A11 (0.35) | BMP1CAPN1FCER2 | |
| SCHEMBL6600536 | 0.86 | SLC7A11 (0.34) | FCER2KMT2AMEN1 | |
| SCHEMBL6601402 | 0.79 | CAPN1 (0.39) | CAPN1FCER2CTSLCTSB | |
| SCHEMBL4282444 | 0.79 | CAPN1 (0.39) | CAPN1FCER2CTSLCTSB | |
| SCHEMBL6601083 | 0.78 | MC4R (0.41) | SMN1; SMN2BMP1NR1H4CYP1A2CYP2D6 | |
| SCHEMBL8579403 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2BMP1NR1H4CYP1A2CYP2D6 | |
| SCHEMBL4284133 | 0.76 | MAOB (0.37) | SMN1; SMN2BMP1CAPN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |