Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760 | 0.79 | CA12 (0.41) | CYP2C19CYP1A2 | |
| SCHEMBL2707882 | 0.79 | SMN1; SMN2 (0.33) | LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL712601 | 0.79 | SMN1; SMN2 (0.33) | LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL14567507 | 0.77 | CAD (0.33) | LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL275494 | 0.74 | SMN1; SMN2 (0.36) | LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL25863400 | 0.74 | SMN1; SMN2 (0.36) | LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL33527021 | 0.73 | ALOX15 (0.34) | CYP2C19CYP1A2SMN1; SMN2 | |
| SCHEMBL3026701 | 0.73 | CTSC (0.35) | — | |
| SCHEMBL11395544 | 0.71 | DGAT1 (0.33) | LMNACYP2C19 | |
| SCHEMBL3105952 | 0.71 | CA1 (0.40) | CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066316-B1 | CINNAMIC ACID DERIVATIVES HAVING CELL ADHESION MODULATING ACTIVITY | CELLTECH THERAPEUTICS LTD (GB) | 2004-05-12 | — | — | EP | disclosed |
| EP-1095036-B1 | CINNAMIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH THERAPEUTICS LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-6465471-B1 | INHIBIT BINDING OF ALPHA 4 INTEGRINS TO THEIR LIGANDS THUS THEY ARE OF USE IN PROPHYLAXIS AND TREATMENT OF IMMUNE OR INFLAMMATORY DISORDERS | CELLTECH THERAPEUTICS LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |