Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715642 | 0.77 | LMNA (0.33) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL4457586 | 0.77 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL7628951 | 0.76 | SMN1; SMN2 (0.34) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL29330514 | 0.75 | LMNA (0.39) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL15412358 | 0.75 | LMNA (0.39) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL1009541 | 0.73 | LMNA (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL6116656 | 0.73 | LMNA (0.37) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL6599558 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13264615 | 0.71 | LMNA (0.36) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL11687600 | 0.71 | LMNA (0.36) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915833-B1 | FLUORINATION OF KETOAMIDES | F2 CHEMICALS LTD (GB) | 2004-05-12 | — | — | EP | disclosed |
| US-6388133-B1 | Fluorination of ketoamides | F2 CHEMICALS LIMITED (GB) | 2002-05-14 | — | — | US | disclosed |
| EP-0915833-A1 | FLUORINATION OF KETOAMIDES | F2 Chemicals Ltd. (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005628-A1 | FLUORINATION OF KETOAMIDES | F2 CHEMICALS LIMITED (GB) | 1998-02-12 | — | — | WO | disclosed |