SCHEMBL1009541

SCHEMBL1009541

CCN(CC)C(=O)C(F)Cl

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
DPP4 P27487 1/20 0.33
HTT P42858 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
MC4R P32245 1/20 0.31
MLYCD O95822 1/20 0.31
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457586 0.79 LMNA (0.40) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL11897019 0.79 LMNA (0.40) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL2921860 0.77 LMNA (0.39) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL10671732 0.77 LMNA (0.39) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL10673924 0.77 LMNA (0.39) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL29330514 0.77 LMNA (0.39) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL6314367 0.75 LMNA (0.37) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL6601203 0.73 LMNA (0.36) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL3338152 0.73 LMNA (0.36) LMNAALDH1A1MMP1MMP2MMP3
SCHEMBL1906173 0.71 MLYCD (0.36) LMNAALDH1A1MMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268601-B1 METHOD FOR PREPARING DIFLUOROACETIC ACID AND SALTS THEREOF RHODIA OPERATIONS (FR) 2014-09-17 EP disclosed
US-8299300-B2 Method for preparing difluoroacetic acid and salts thereof RHODIA OPERATIONS (FR) 2012-10-30 US disclosed
US-20110065955-A1 Method For Preparing Difluoroacetic Acid and Salts Thereof RHODIA OPERATIONS (FR) 2011-03-17 US disclosed
EP-2268601-A1 METHOD FOR PREPARING DIFLUOROACETIC ACID AND SALTS THEREOF Rhodia Opérations (FR) 2011-01-05 EP disclosed
WO-2009115426-A1 METHOD FOR PREPARING DIFLUOROACETIC ACID AND SALTS THEREOF RHODIA OPERATIONS (FR) 2009-09-24 WO disclosed